OneCareAI: New AI-Powered BSC spinoff aims to revolutionize stroke prevention

• OneCareAI, a spin-off conceived within the European AI-SPRINT project and currently driven by Innostroke, leverages artificial intelligence and high-performance computing to detect stroke risk early using electrocardiograms collected from smartwatches.
• The technology developed also has the potential to be applied to cardiovascular, metabolic, and respiratory diseases. Its target market includes hospitals, insurance companies, medical device manufacturers, and telemedicine platforms.

Barcelona, April 20, 2025 – The Barcelona Supercomputing Center – National Supercomputing Center (BSC) has launched a new spinoff called OneCareAI, focused on the real-time, early, and personalized detection of cerebrovascular disease risk. This initiative is based on technology developed within the Innostroke project, fulfilling one of its main goals: effectively transferring scientific knowledge to the market.

Innostroke is a project funded by the Spanish Recovery, Transformation and Resilience Plan and is part of the National Artificial Intelligence Strategy (ENIA) as well as the so-called Producte and Innovadors programs under the Knowledge Industry programme promoted by the Department of Research and Universities of the Government of Catalonia. With the creation of OneCareAI, BSC strengthens its commitment to innovation in digital health, offering a pioneering solution that brings the benefits of supercomputing and artificial intelligence into everyday life, with the aim of improving prevention and overall well-being.

A pioneering technology based in AI and HPC

OneCareAI was born out of the need to transfer Innostroke technology to the market—a solution developed by Computer and Life Sciences researchers at BSC within the European project AI-Sprint. Backed by The Collider program from the Mobile World Capital (MWC) Foundation, the spinoff has received support from national and local funding agencies through, for example, the Producte and Innovadors programs under the Knowledge Industry programme, promoted by the Department of Research and Universities of the Government of Catalonia. The technology is based on the analysis of electrocardiogram (ECG) data collected through wearable devices like smartwatches, and it integrates lifestyle information via a mobile application. “The constituion of OneCareAI marks an important step in bringing Innostroke technology closer to the market. This solution has been developed using advanced HPC and AI techniques,” says Daniele Lezzi, co-founder of OneCareAI, senior researcher in the Computer Sciences Department at BSC, and the lead developer of Innostroke technology from its origins. Unlike existing solutions, OneCareAI combines multi-omic data with electrocardiogram patterns to deliver much more comprehensive and accurate risk assessments. Moreover, its technology is device-agnostic, ensuring interoperability with a wide range of existing devices on the market.

OneCareAI’s potential market includes hospitals, to improve patient management and monitoring; insurance companies, which can optimize their risk stratification processes; medical device manufacturers, who gain added value by integrating predictive capabilities into electrocardiograms; and telemedicine platforms, by enabling automated diagnostics. The business model is based on B2B subscriptions and co-development agreements with strategic partners in the healthcare sector.

Although OneCareAI initially focuses on the stroke prevention market, its technology has the potential to expand to other cardiovascular, metabolic, and respiratory diseases, opening up broad opportunities for future scalability and development.“OneCareAI represents a new way of understanding preventive healthcare—bridging science, technology, and personal well-being to anticipate cerebrovascular diseases and improve people’s quality of life,” adds Davide Cirillo, co-founder of OneCareAI and Head of the Machine Learning for Biomedical Research Unit in the Life Sciences Department at BSC.

From scientific knowledge to real impact on society

This initiative reflects one of the center’s key commitments: ensuring that scientific knowledge generates real impact in society. OneCareAI’s ultimate goal is to enhance quality of life and collective well-being.

Although the prototype developed within the Innostroke project is still in the testing and technological development phase, it will be showcased at two key innovation ecosystem events: the startup pavilion at the IoT Solutions World Congress and the Health Revolution Congress—both to be held in mid-May in Barcelona.

Thanks to the participation of both researchers in Innovation Journey—a BSC training program that exposes entrepreneurial scientists to new market opportunities—and to the support from national and local funding programs, the transfer of this technology to the market has been successfully accelerated. Innostroke stands as a good example of how BSC fosters the transfer of scientific knowledge and technology into the marketplace, following a structured, effective process that can serve as a model for future initiatives.

The fourteenth spinoff of BSC

With this new spin-off, OneCareAI becomes the fourteenth spinoff created by BSC in its 20-year history—further proof of the center’s strong commitment to transforming scientific innovation into tangible benefits for society. The previous 13 spinoffs currently employ more than 380 highly skilled professionals and have attracted over €40 million in private investment, helping to consolidate a thriving and high-impact innovation ecosystem.

Related news: https://www.bsc.es/news/bsc-news/bsc-develops-ai-model-predict-stroke-risk-using-mobile-devices

The project Innostroke – Innovative Stroke Risk Monitoring with AI is funded by the Spanish Ministry of Digital Transformation and Civil Service within the framework of the 2024 Artificial Intelligence Strategy and the Recovery, Transformation and Resilience Plan – funded by the European Union – NextGenerationEU.

The OneCareAI project has received funding from the Knowledge Industry program, Product Modality B and Innovators Modality C, granted by the Agency for the Management of University and Research Grants (AGAUR) of the Government of Catalonia.